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Outcome of a HIV Positive Patient Infected with COVID-19 after an Autologous Bone Marrow Transplantation: A Case Report

Author(s):

Masoud Mardani, Athena Sharifi-Razavi, Shirin Sheibani and Mana Baziboroun*  

Abstract:


Background: The World Health Organization (WHO) announced the SARS-COV-2 disease pandemic on March 9, 2020.With the advent of this disease, another health burden was added to about 37.9 million people in the world who are infected with HIV and are suffering from various diseases. These people may be at serious risk of covid-19. Information about the effects of Covid-19 on people living with HIV, is limited.

Case presentation: We reported a 61-year-old man who was a known case of HIV from 6 years ago that was being treated with HAART (highly active antiretroviral therapy). He also had a history of Hodgkin’s lymphoma from 4 years ago who underwent autologous bone marrow transplantation (BMT) 2 weeks before given referral to our hospital. He complained of weakness, anorexia, and fever. RT-PCR for SARS-COV-2-RNA was positive in his nasopharyngeal and oropharyngeal swab. He was diagnosed with COVID-19 infection and treated with atazanavir. After one week, the patient discharged in a good general state.

Conclusion: To the best of our knowledge, it is the first report of COVID-19 infection in an HIV positive patient after BMT in Iran. Despite his immunodeficiency, COVID-19 disease had mild manifestations and he had a good prognosis. We hope that our report and that of others can remain promising to doctors and HIV patients cross fingers for COVID-19 recovery.

Keywords:

COVID-19, HIV, Bone marrow transplant, Hodgkin lymphoma, Atazanavir, SARS-COV-2

Affiliation:

Infectious Diseases and Tropical Medicine Research Center, ShahidBeheshti University of Medial Sciences, Tehran, Clinical Research Development Unit of Bou-Ali Sina Hospital, Mazandarn University of Medical Science, Sari, Student Research Committee, School of Medicine, Mazandaran, University of Medical Sciences, Sari, Infectious Diseases and Tropical Medicine Research Center, ShahidBeheshti University of Medial Sciences, Tehran



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