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Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

[ Vol. 4 , Issue. 1 ]


Giuseppe Barbaro   Pages 79 - 85 ( 7 )


Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.


Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease


Viale Anicio Gallo 63,00174 Rome, Italy.

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