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Prevention of sudden cardiac death in persons living with HIV infection

Author(s):

Jean-Jacques Monsuez* and Marilucy Lopez-Sublet  

Abstract:


Persons living with HIV infection (PLWH) have been recognized to have an increased risk of sudden cardiac death (SCD). Prevention of this risk should theoretically be included in their long-term management. However, only a few approaches have been proposed to optimize such interventions. Targeting detection of the commonly associated conditions such as coronary artery disease, left ventricular dysfunction, heart failure, QT interval prolongation and ventricular arrhythmias is the first step of this prevention. However, although detection of the risk of SCD is a suitable challenge in PLWH, it remains uncertain whether optimized treatment of the identified risks would unequivocally translate into a decrease in SCD rates.

Keywords:

HIV, sudden cardiac death, cardiovascular risk factors, atherosclerosis, arrhythmia, prevention

Affiliation:

Cardiology, Hôpital René Muret, Hôpitaux Universitaires de Paris Seine Saint-Denis, Center of Hypertension, Hôpital Avicenne, Hôpitaux Universitaires de Paris Seine Saint-Denis



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